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Machine Learning Derived MRI Based Biomarker for Alzheimer’s Disease
Vincent Mok 教授是香港中文大學威爾斯親王醫院內科及治療學系神經科教授。的研究聚焦在了解失智症機轉及預防失智症的方法,神經心理學工具在血管性認知障礙評估中的驗證、血管性認知障礙的神經影像學等。 他是第一個報告亞洲腦部小血管疾病(CSVD)與認知障礙關聯的人,並率先報告了在亞洲華人社區盛行率,提高人們對治CSVD的策略意識(例如血壓控制)。他進行大規模研究調查。研究中風後的認知能力下降,發現同時存在澱粉樣蛋白斑塊和 CSVD 是中風後早期和延遲認知衰退的重要因子。 這些發現為預防血管性認知障礙提供了途徑。他在同儕評審的國際期刊上發表了超過 300 篇文章,著作刊登在許多重要期刊如 Lancet, JAMA、Lancet Neurology、Nature Reviews Neurology、Alzheimer’s & Dementia、JAMA Neurology、JAMA Psychiatry、Journal of Neurology, Neurosurgery and Psychiatry (JNNP), Annals of Neurology, Neurology 和 Stroke。

Prof. Vincent Mok is Professor of Neurology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong. His research focuses on understanding the mechanisms of dementia and to investigate strategies that may help to prevent dementia. He is the first to report the association of cerebral small vessel disease (CSVD) and cognitive impairment in Asia and the first to report the community prevalence of CSVD among Asians (Chinese). Such findings have significantly increased the awareness that strategies targeting CSVD (e.g. blood pressure lowering) can help to prevent dementia in this region, where the burden of dementia is particularly huge. Prof. Mok conducted one of the largest single-centre studies investigating the prevalence and mechanisms of early and delayed cognitive decline in the context of stroke and found that concurrent presence of amyloid plaques as detected by in-vivo amyloid PET imaging and CSVD are important factors associated with early and delayed cognitive decline after stroke, respectively. Such findings provide a road map of how to prevent vascular cognitive impairment.
Prof. Mok has authored more than 400 publications in peer-reviewed international journals (with book chapters), with publications at Lancet, JAMA, Lancet Neurology, Nature Reviews Neurology, Alzheimer’s & Dementia, JAMA Neurology, JAMA Psychiatry, Journal of Neurology, Neurosurgery and Psychiatry (JNNP), Annals of Neurology, Neurology and Stroke.

演講者

Prof. Vincent C.T. Mok

Master of S.H. Ho College
Mok Hing Yiu Professor of Medicine
Division of Neurology, Department of Medicine and Therapeutics
Faculty of Medicine
The Chinese University of Hong Kong

時間

Feb 24, 2023, 12:30~13:30 (會議室串流將於中午12:20開啟)

地點

當日請直接至YouTube頻道參與,簽到表置頂於聊天室

Youtube Link

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語言

英文 

TNS/TDS/TSGP /附醫CFD積分/北醫大教職員時數認列申請中。